Hydrochloric Acid → HCID 20483506, compound

Participants

Reaction Steps

A solution of 45 g of crude 3-methyl-2-{[2-phenyl-3-(4-phenyl-2-butyl)-oxazolidin-5-yl]-methoxy}-pyridine in 200 ml of ethanol is hydrolysed with 120 ml of 4 N hydrochloric acid for 3 hours at 20° C. analogously to Example 31, and the mixture is worked up. Distillation in a bulb tube at 140°-150° C./0.04 mm Hg gives 2-[2'-hydroxy-3'-(1-methyl-3-phenyl-propylamino)-propoxy]-3-methyl-pyridine as a light yellow oil.

Provenance & Evidence