HuagongsheHuagongshe Chemistry Print Report · For research reference only
Allyl bromide → 5-Allyloxy-2-methylthiopyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Allyl bromide | HCID 7841 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-(Methylsulfanyl)pyrimidin-5-ol | HCID 588357 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 5-Allyloxy-2-methylthiopyrimidine | HCID 20483481 | — |
Reaction Steps
4.5 g of 5-hydroxy-2-methylthiopyrimidine, 9.0 g of potassium carbonate and 3.9 g of allyl bromide are together refluxed in 50 ml of acetone, with stirring, for 41/2 hours. The inorganic salts are removed by filtration, and the filtrate is concentrated under reduced pressure. The oil remaining yields, from petroleum ether, 5-allyloxy-2-methylthiopyrimidine, m.p. 41°-42°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04195090 |
| Source dataset | uspto-grants-1980_03 |
| ORD ID | ord-4a63a30835ec4ac4a34a686e497a7d84 |
| Source note | uspto-grants-1980_03 |