Phenol → HCID 1811246, compound

HRID 1701768Notes

Reaction equation

HRID 1701768 reaction equation
CCOCC.[C:6]1([OH:12])[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1.[C:13]1([C:19]2[O:20][CH2:21][CH2:22][N:23]=2)[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>O>[C:13]1([C:19]([NH:23][CH2:22][CH2:21][O:12][C:6]2[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=2)=[O:20])[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

5

Reactant 3

HCID 996PhenolHCID 3283Diethyl EtherHCID 2440302-Phenyl-2-oxazoline

Product 1

HCID 1811246HCID 1811246, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

In German Pat. No. 1,062,253, A. Jager describes the preparation of various ether and carboxamide compounds by treating certain substituted oxazolines with certain phenols, with the exclusion of water. A mixture of phenol and 2-phenyloxazoline refluxed for 7 hours yielded PhCONHCH2CH2OPh as a product. Similarly, p-bis(oxazolinyl)benzene and phenol gave N,N'-bis(β-phenoxyethyl)terephthalamide. Finally, Jager found that a mixture of 2-phenyl-2-oxazoline and hydroquinone produced 1,4-bis(β-benzamidoethoxy)benzene.

Workup

  1. temperaturerefluxed for 7 hours

Sources & evidence

ORD record
ord-83c959c1128d489ebd1372c345d835ab
Source dataset
uspto-grants-1980_03
Patent number
US04195154

Reaction notes

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