HCID 15610185, compound → HCID 20332295, compound

HRID 1701782Notes

Reaction equation

NC(CCCCCCCCC(N)CCC)CCC.C(C1CC=CCCC=CCC(CCC)N=N1)CC.[CH:37]1([CH:44]2[CH2:55][CH:54]=[CH:53][CH2:52][CH2:51][CH:50]=[CH:49][CH2:48][CH:47]([CH:56]3[CH2:62][CH2:61][CH2:60][CH2:59][CH2:58][CH2:57]3)[N:46]=[N:45]2)[CH2:43][CH2:42][CH2:41][CH2:40][CH2:39][CH2:38]1>>[NH2:45][CH:44]([CH:37]1[CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][CH2:43]1)[CH2:55][CH2:54][CH2:53][CH2:52][CH2:51][CH2:50][CH2:49][CH2:48][CH:47]([NH2:46])[CH:56]1[CH2:62][CH2:61][CH2:60][CH2:59][CH2:58][CH2:57]1

Participants

Reactant 3

HCID 15610185HCID 15610185, compound

HCID 56615476HCID 56615476, compound

HCID 57129806HCID 57129806, compound

Product 1

HCID 20332295HCID 20332295, compound

Procedure

If there are used in the manner described under (a), instead of 942 g (3.79 mols) of 3,12-dipropyl-1,2-diaza-1,5,9-cyclododecatriene, 106 g (0.3 mol) of 3,12-dicycloheptyl-1,2-diaza-1,5,9-cyclododecatriene (diastereoisomeric mixture) and correspondingly reduced amounts of catalyst and solvent, with otherwise the same procedure, there is obtained, after chromatographic purification, and 63 g (58% of theory) of 1,10-diamino-1,10-dicycloheptyldecane as colourless oil [nD20 =1.5018; IR (liquid) inter alia bands at 3390, 3310 and 3618 cm-1 ].

Workup

customwith otherwise the same procedure, there is obtained
customafter chromatographic purification, and 63 g (58% of theory) of 1,10-diamino-1,10-dicycloheptyldecane as colourless oil [nD20 =1.5018; IR (liquid) inter alia bands at 3390, 3310 and 3618 cm-1 ]

Sources & evidence

ORD record: ord-78cb617555c24814855690efdbb611f4
Source dataset: uspto-grants-1980_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04195165

Reaction notes

Loading…