HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Propanol → N-Methyl-D-glucamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Propanol | HCID 1031 | — |
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | 1-Pentanol | HCID 6276 | — |
| Reactant | (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal | HCID 107526 | — |
| Solvent | Water | HCID 962 | — |
| Product | N-Methyl-D-glucamine | HCID 8567 | — |
Reaction Steps
20 g of polifungin and 6 g of glucose were dissolved in 100 ml of dimethyl formamide and then the procedure was carried out as in the Example V, but instead of n-amyl alcohol there was used n-propyl alcohol in the same quantity as n-amyl one. 16.0 g of N-methylglucamine salt of N-glycosyl polifungin, soluble in water, of biological activity of 2010 U/mg, E1 cm1% =558 at 304 nm were obtained. Original antibiotic: E1 cm1% =720 at 304 nm.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04195172 |
| Source dataset | uspto-grants-1980_03 |
| ORD ID | ord-7307a136b4e14338b0be6f4cd5f4f192 |
| Source note | uspto-grants-1980_03 |