HuagongsheHuagongshe Chemistry Print Report · For research reference only
beta-Maltose → N-Methyl-D-glucamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | beta-Maltose | HCID 6255 | — |
| Reactant | 1400-61-9 | HCID 44424838 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-Methyl-D-glucamine | HCID 8567 | 427% |
Reaction Steps
5 g of nystatin and 3.0 g of maltose were suspended in 50 ml of dimethyl formamide and next the procedure was carried out as in Example IV. 4.5 g of N-methylglucamine salt of N-glycosyl nystatin of E1 cm1% =580 at 304 nm and IC50 =0.45 mcg/ml were obtained. Original antibiotic exhibited: E1 cm1% =790 at 304 nm and IC50 =0.18 mcg/ml.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04195172 |
| Source dataset | uspto-grants-1980_03 |
| ORD ID | ord-dc1ac723d53c486abc1cf5010f12e1e9 |
| Source note | uspto-grants-1980_03 |