HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 5-[(Diethylamino)methyl]-2-furancarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Butyl 5-[(diethylamino)methyl]furan-2-carboxylate | HCID 20346152 | — |
| Product | 5-[(Diethylamino)methyl]-2-furancarboxamide | HCID 43132183 | — |
Reaction Steps
A mixture of 25.3 g (0.1 mole) of n-butyl 5-(N,N-diethylaminomethyl)-2-furoate is added to 50 ml of liquid ammonia in a pressure vessel. The mixture is held at 180° C. and 2000 pounds per square inch gage pressure for 8 hours. The mixture is cooled to ambient temperature and evaporated to dryness giving 5-(N,N-diethylaminomethyl)-2-furamide (m.p. 164°-165° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04195023 |
| Source dataset | uspto-grants-1980_03 |
| ORD ID | ord-eb85caa288a540a391469828a5b38c70 |
| Source note | uspto-grants-1980_03 |