Ammonia → HCID 178448903, compound

HRID 1701843Notes

Reaction equation

HRID 1701843 reaction equation
[NH2:1][C:2]1[C:6]2[C:7]([Cl:11])=[CH:8][CH:9]=[CH:10][C:5]=2[S:4](=[O:13])(=[O:12])[N:3]=1.[CH2:14](N)[CH2:15][CH2:16][CH3:17].N>O1CCOCC1>[CH2:14]([NH:1][C:2]1[C:6]2[C:7]([Cl:11])=[CH:8][CH:9]=[CH:10][C:5]=2[S:4](=[O:13])(=[O:12])[N:3]=1)[CH2:15][CH2:16][CH3:17]

Participants

5

Reactant 3

HCID 222AmmoniaHCID 8007ButylamineHCID 14770684HCID 14770684, compound

Product 1

HCID 178448903HCID 178448903, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

A solution of 2.17 g of the 3-amino-4-chlorobenzo[d]isothiazole-1,1-dioxide prepared according to Example II and 2 ml of n-butylamine in 15 ml of dioxane was boiled for approx. 2 hours, ammonia escaping. After distilling off the solvent, the residue was stirred with water, sucked off, washed successively with water and petroleum ether and dried. The desired product was obtained in a yield of 2.4 g, melting-point 136°-138° C.

Workup

  1. distillationAfter distilling off the solvent
  2. washwashed successively with water and petroleum ether
  3. customdried

Sources & evidence

ORD record
ord-876a4bfa40dd45dd9e0b84a06a7605ac
Source dataset
uspto-grants-1983_04
Patent number
US04379157

Reaction notes

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