Acetic Acid → HCID 70083960, compound

Participants

Reaction Steps

To the 9-[3-(3,5-cis-dimethylpiperazino)propyl]-carbazole (10 g) of Example 4 dissolved in hot toluene (70 ml) was added acetic acid (2.0 ml). The mixture was stirred and cooled to 2°. The resulting product was collected by filtration, washed with cyclohexane (35 ml) and dried under reduced pressure to give cis-9-[3-(3,5-dimethyl-1-piperazinyl)propyl]carbazole acetate one-quarter hydrate (10.4 g), m.p. 144°-146°, which had the following elemental analysis:

Provenance & Evidence