Ammonia → HCID 13120747, compound

Participants

Reaction Steps

Heating a mixture of 0.8 g (2.1 mmol) of 8-chloro-6-phenyl-2H,4H-pyrazolo[3,4-d][2]benzazepine-2-acetic acid ethyl ester and 20 ml of methanolic ammonia (ca. 20%, v/v) in an autoclave on the steam bath for 20 hr gave after crystallization from ethyl acetate/ether colorless crystals with mp 236°-238°. The analytical sample was recrystallized from ethyl acetate/methylene chloride/ether.

Provenance & Evidence