Pyridine → HCID 15580738, compound

HRID 1701950Notes

Reaction equation

HRID 1701950 reaction equation
[CH3:1][O:2][C:3]1[CH:11]=[CH:10][CH:9]=[C:5]([C:6]([OH:8])=[O:7])[C:4]=1N.[C:13]([O:16][C:17]1[CH:25]=[CH:24][C:20]([C:21](Cl)=O)=[CH:19][CH:18]=1)(=[O:15])[CH3:14].[N:26]1C=CC=CC=1>>[C:13]([O:16][C:17]1[CH:25]=[CH:24][C:20]([C:21]2[O:8][C:6](=[O:7])[C:5]3[CH:4]=[C:3]([O:2][CH3:1])[CH:11]=[CH:10][C:9]=3[N:26]=2)=[CH:19][CH:18]=1)(=[O:15])[CH3:14]

Participants

4

Reactant 3

HCID 1049PyridineHCID 2557202-Amino-3-methoxybenzoic acidHCID 2756254p-Acetoxybenzoyl chloride

Product 1

HCID 15580738HCID 15580738, compound

Procedure

16.7 gm (0.1 mol) of 3-methoxy-anthranilic acid were dissolved in 100 ml of pyridine, and the solution was mixed, while cooling and stirring, with 23.8 gm (0.1 mol+20%) of 4-acetoxy-benzoyl chloride. After 2 hours the reaction was finished, and the reaction mixture was poured into ice water. The precipitate thus obtained was suction-filtered off, dried and recrystallized from methanol.

Workup

  1. additionthe solution was mixed
  2. temperaturewhile cooling
  3. customThe precipitate thus obtained
  4. filtrationwas suction-filtered off
  5. customdried
  6. customrecrystallized from methanol

Sources & evidence

ORD record
ord-d8039fa4c7c74142819ec8e0a5537dd7
Source dataset
uspto-grants-1983_04
Patent number
US04379788

Reaction notes

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