HCID 13121256, compound → HCID 13121257, compound

Participants

Reaction Steps

2,3-Diphenylpyrazolidin (133.9 g, 620 mmoles, described in Example 1) is dissolved in methanol (1.7 liters) and the solution is heated at 60° C. in the presence of Raney nickel (37 g) under 50 atmospheres of hydrogen for 5 hr. The catalyst is removed by filtration through diatomaceous earth and the filtrate is evaporated. The residue is crystallized from cyclohexane-hexane to give the title compound (48.4 g) mp 104°-105° C.

Provenance & Evidence