Bromine → HCID 13048613, compound

HRID 1702000Notes

Reaction equation

HRID 1702000 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[CH:9]([S:17]([C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1)(=[O:19])=[O:18])[CH2:10][C:11](=[O:16])[C:12]([CH3:15])([CH3:14])[CH3:13].[Br:26]Br>C(Cl)(Cl)Cl>[Br:26][CH:10]([C:11](=[O:16])[C:12]([CH3:14])([CH3:15])[CH3:13])[CH:9]([C:3]1[CH:4]=[CH:5][C:6]([Cl:8])=[CH:7][C:2]=1[Cl:1])[S:17]([C:20]1[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=1)(=[O:19])=[O:18]

Participants

4

Reactant 2

HCID 24408BromineHCID 13048713HCID 13048713, compound

Product 1

HCID 13048613HCID 13048613, compoundYield 93.1%

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

To a solution of 39.9 g of 1-(2,4-dichlorophenyl)-4,4-dimethyl-1-phenylsulfonylpentan-3-one in 500 ml of chloroform, 16.8 g of bromine was added dropwise at 60° C. and the mixture was then kept at 60° C. for 4 hours. The reaction mixture was treated in the same way as that of Example 3 to give 44.5 g of crystals of the captioned compound. m.p. 135°-136° C.

Workup

  1. additionThe reaction mixture was treated in the same way as that of Example 3

Sources & evidence

ORD record
ord-0b4cfdfeaac54e6c90c45161dac973ae
Source dataset
uspto-grants-1983_04
Patent number
US04379921

Reaction notes

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