HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic anhydride → 7-(2-Methoxyimino-3-oxo-bromobutyramido)-3-cephem-4-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic anhydride | HCID 9845 | — |
| Reactant | 7-(2-Methoxyimino-3-oxo-4-bromobutyramido)-3-hydroxycepham-4-carboxylic acid | HCID 86738091 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 7-(2-Methoxyimino-3-oxo-bromobutyramido)-3-cephem-4-carboxylic acid | HCID 131712504 | 67.9% |
Reaction Steps
Trifluoroacetic anhydride (1 ml.) was added to a solution of 7-(2-methoxyimino-3-oxo-4-bromobutyramido)-3-hydroxycepham-4-carboxylic acid (syn isomer, 1 g.) in tetrahydrofuran (3 ml.) and the mixture was treated in a similar manner to that of Example 18 to give 7-(2-methoxyimino-3-oxo-4-bromobutyramido)-3-cephem-4-carboxylic acid (syn isomer, 0.65 g.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04379922 |
| Source dataset | uspto-grants-1983_04 |
| ORD ID | ord-ad8bf5fbd8d745f7912eee8a7f6c616d |
| Source note | uspto-grants-1983_04 |