HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloroform → 1-Chloro-2-isocyano-3-methylbenzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloroform | HCID 6212 | — |
| Reactant | 2-Chloro-6-methylaniline | HCID 6897 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Catalyst | Benzyl triethylammonium chloride | HCID 66133 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 1-Chloro-2-isocyano-3-methylbenzene | HCID 16217466 | — |
Reaction Steps
The procedure of Example 1 was again followed, using 100 g (0.7 mole) of 2-methyl-6-chloroaniline, 75 ml of chloroform, 100 ml of methylene chloride, 175 ml of 50% aqueous sodium hydroxide, and 1 g of benzyltriethylammonium chloride. The product was a solid weighing 44 g, with structure confirmed by mass spectroscopy.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04380468 |
| Source dataset | uspto-grants-1983_04 |
| ORD ID | ord-8d48991346e645769c5802957fe443aa |
| Source note | uspto-grants-1983_04 |