HCID 12942918, compound → HCID 12942917, compound

HRID 1702145Notes

Reaction equation

COC(C1C(C2N=C(C3C=CC=CC=3)SC=2)C(C(OC)=O)=C(C)NC=1C)=O.[CH:28]([O:31][C:32]([C:34]1[CH:39]([C:40]2[N:41]=[C:42]([C:45]3[CH:50]=[CH:49][CH:48]=[CH:47][CH:46]=3)[S:43][CH:44]=2)[C:38]([C:51]([O:53][CH:54](C)[CH3:55])=[O:52])=[C:37]([CH3:57])[NH:36][C:35]=1[CH3:58])=[O:33])(C)[CH3:29].C(OC(C1C(C2N=C(C3C=CC=CC=3)SC=2)C(C(OCCCC)=O)=C(C)NC=1C)=O)CCC>>[CH2:28]([O:31][C:32]([C:34]1[CH:39]([C:40]2[N:41]=[C:42]([C:45]3[CH:50]=[CH:49][CH:48]=[CH:47][CH:46]=3)[S:43][CH:44]=2)[C:38]([C:51]([O:53][CH2:54][CH3:55])=[O:52])=[C:37]([CH3:57])[NH:36][C:35]=1[CH3:58])=[O:33])[CH3:29]

Participants

Reactant 3

HCID 12942918HCID 12942918, compound

HCID 12942919HCID 12942919, compound

HCID 12942920HCID 12942920, compound

Product 1

HCID 12942917HCID 12942917, compound

Procedure

The following compounds were obtained in an analogous manner: (b) 2,6-dimethyl-4-(2'-phenylthiazol-4-yl)-1,4-dihydropyridine-3,5-dicarboxylic acid dimethyl ester, (c) 2,6-dimethyl-4-(2'-phenylthiazol-4-yl)-1,4-dihydropyridine-3,5-dicarboxylic acid diisopropyl ester and (d) 2,6-dimethyl-4-(2'-phenylthiazol-4-yl)-1,4-dihydropyridine-3,5-dicarboxylic acid dibutyl ester.

Workup

customThe following compounds were obtained in an analogous manner

Sources & evidence

ORD record: ord-0faab6c730bb4e2886ff3a41c661ebd5
Source dataset: uspto-grants-1983_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04380547

Reaction notes

Loading…