HuagongsheHuagongshe Chemistry Print Report · For research reference only
Iodoethane → tert.-butyl (4S)-1-ethyl-3-benzyloxycarbonyl-2-oxo-imidazolidine-4-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Iodoethane | HCID 6340 | — |
| Reactant | 1-benzyl 5-tert-butyl (5S)-2-oxoimidazolidine-1,5-dicarboxylate | HCID 11067160 | — |
| Catalyst | Silver(II) oxide | HCID 92152 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | tert.-butyl (4S)-1-ethyl-3-benzyloxycarbonyl-2-oxo-imidazolidine-4-carboxylate | HCID 13053979 | 59.4% |
Reaction Steps
9.6 g of tert.-butyl (4S)-3-benzyloxycarbonyl-2-oxo-imidazolidine-4-carboxylate, 14.0 g of silver oxide, 46.8 g of ethyl iodide and 200 ml of dimethylformamide are treated in the same manner as described in Example 1-(2). 6.2 g of tert.-butyl (4S)-1-ethyl-3-benzyloxycarbonyl-2-oxo-imidazolidine-4-carboxylate are obtained as colorless crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04380644 |
| Source dataset | uspto-grants-1983_04 |
| ORD ID | ord-33e0326f897d4d1d825a00def4778bbc |
| Source note | uspto-grants-1983_04 |