HCID 178479412, compound → HCID 178482518, compound

HRID 1702270Notes

Reaction equation

HRID 1702270 reaction equation
[CH3:1][NH:2][C:3]1[C:7](CCS)=[N:6][S:5](=[O:12])(=[O:11])[N:4]=1.Cl.Cl[CH2:15][C:16]1[N:17]=[C:18]([NH:21][C:22]([NH2:24])=[NH:23])[S:19][CH:20]=1>>[NH:21]([C:18]1[S:19][CH:20]=[C:16]([CH2:15][S:19][CH2:20][CH2:16][NH:17][C:7]2[C:3]([NH:2][CH3:1])=[N:4][S:5](=[O:11])(=[O:12])[N:6]=2)[N:17]=1)[C:22]([NH2:24])=[NH:23]

Participants

3

Reactant 2

HCID 178479412HCID 178479412, compoundHCID 178482509HCID 178482509, compound

Product 1

HCID 178482518HCID 178482518, compound

Procedure

When a solution of 3-methylamino-4-(2-mercaptoethyl)-1,2,5-thiadiazole 1,1-dioxide [prepared in Example 25, Step A] is reacted with 4-chloromethyl-2-guanidinothiazole hydrochloride and a strong base, the title compound is thereby produced, which is identical to the product obtained in Example 31.

Sources & evidence

ORD record
ord-b881fba8cced4653b14a108448f09a79
Source dataset
uspto-grants-1983_04
Patent number
US04380638

Reaction notes

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