HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cysteamine → 3-{2-[(2-Dimethylaminomethyl-4-thiazolyl)methylthio]ethylamino}-4-methylamino-1,2,5-thiadiazole 1-oxide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cysteamine | HCID 6058 | — |
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | (2-((Dimethylamino)methyl)thiazol-4-yl)methanol | HCID 1838020 | — |
| Reactant | 3,4-Dimethoxy-1,2,5-thiadiazole 1-oxide | HCID 12913947 | — |
| Reactant | 3-Methylamino-4-(2-mercaptoethyl)-1,2,5-thiadiazole 1-oxide | HCID 20402074 | — |
| Product | 3-{2-[(2-Dimethylaminomethyl-4-thiazolyl)methylthio]ethylamino}-4-methylamino-1,2,5-thiadiazole 1-oxide | HCID 15964146 | — |
Reaction Steps
Reaction of 3-methylamino-4-(2-mercaptoethyl)-1,2,5-thiadiazole 1-oxide [prepared by reacting 3,4-dimethoxy-1,2,5-thiadiazole 1-oxide with 2-aminoethanethiol and methylamine according to the procedure described in Example 25, Step A] with about one equivalent of 2-dimethylaminomethyl-4-hydroxymethylthiazole [prepared in Example 34, Step D], produces the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04380639 |
| Source dataset | uspto-grants-1983_04 |
| ORD ID | ord-bc07720612b24213bdc565cd3176ddc1 |
| Source note | uspto-grants-1983_04 |