HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Nitrophenol → HCID 2966316, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Nitrophenol | HCID 11137 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | N-3-Bromopropylphthalimide | HCID 21611 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 2966316 | HCID 2966316 | 75.8% |
Reaction Steps
A partial suspension of m-nitrophenol (6.0 g; 43.0 mmoles), N-(3-bromopropyl)phthalimide (10.0 g; 37.0 mmoles) and potassium carbonate (8.0 g; 58.0 mmoles) in 50 ml of DMF was stirred at ambient temperature for 70 hours. The reaction mixture was diluted with 80 ml of water and filtered to give product. Recrystallization from 2-methoxyethanol yielded 9.15 g of the title compound, mp 149°-152°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04380639 |
| Source dataset | uspto-grants-1983_04 |
| ORD ID | ord-089e26d8d2d04d4aa4e7984937bafd7a |
| Source note | uspto-grants-1983_04 |