反应详情

温度

170 °C

A mixture of aniline hydrochloride (13.0 g, 0.10 mole), 3-methyl-2-oxazolidinone (11.0 g, 0.109 mole) and 35 ml of 2-(2-methoxyethoxy)ethanol was heated to 170° C. in an oil bath. The reaction mixture became homogenous and carbon dioxide evolution occurred on heating. After 17 hours, the reaction was allowed to cool to room temperature. After a workup procedure similar to that described in Example 1 and distillation at 105° C. to 110° C. (0.4 mm), an 81 percent distilled yield of the product was obtained as a clear liquid. Product confirmation was made by the use of spectra evidence.

1. temperatureon heating
2. temperatureto cool to room temperature
3. distillationAfter a workup procedure similar to that described in Example 1 and distillation at 105° C. to 110° C. (0.4 mm)
4. distillationan 81 percent distilled yield of the product
5. customwas obtained as a clear liquid