tert-butyl 4-(5-chloro-2,3-dihydro-6-methyl-2-oxo-1H-benzo[d]imidazol-1-yl)-1-piperidinecarboxylate → 5-chloro-6-methyl-1-(piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one

HRID 170257Notes

Reaction equation

HRID 170257 reaction equation
[Cl:1][c:2]1[cH:3][c:4]2[c:5]([n:6]([CH:10]3[CH2:11][CH2:12][N:13]([C:16]([O:17][C:18]([CH3:19])([CH3:20])[CH3:21])=[O:22])[CH2:14][CH2:15]3)[c:7](=[O:9])[nH:8]2)[cH:23][c:24]1[CH3:25].[F:26][c:27]1[c:28]([CH3:29])[cH:30][c:31]2[n:32]([CH:33]3[CH2:34][CH2:35][NH:36][CH2:37][CH2:38]3)[c:39](=[O:40])[nH:41][c:42]2[cH:43]1>>[Cl:1][c:2]1[cH:3][c:4]2[c:5]([n:6]([CH:10]3[CH2:11][CH2:12][NH:13][CH2:14][CH2:15]3)[c:7](=[O:9])[nH:8]2)[cH:23][c:24]1[CH3:25]

Participants

3

Reactant 2

HCID 59850181tert-butyl 4-(5-chloro-2,3-dihydro-6-methyl-2-oxo-1H-benzo[d]imidazol-1-yl)-1-piperidinecarboxylateHCID 598502105-Fluoro-6-methyl-1-(4-piperidinyl)-1,3-dihydro-2H-benzimidazol-2-one

Product 1

HCID 598501975-chloro-6-methyl-1-(piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one

Sources & evidence

ORD record
ord-065b8f1d75234ae498223a59121d1fee
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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