HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(t-Butyldimethylsilyl)-4-(2-acetoxypropyl)-2-azetidinone → 4-(2-Acetoxypropyl)-2-azetidinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(t-Butyldimethylsilyl)-4-(2-acetoxypropyl)-2-azetidinone | HCID 14328990 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-(2-Acetoxypropyl)-2-azetidinone | HCID 14328991 | — |
Reaction Steps
1-(t-butyldimethylsilyl)-4-(2-acetoxypropyl)-2-azetidinone (2.4 g) is dissolved in a solution of HCl in MeOH (0.25 N, 10 ml) and allowed to stand 2.5 hours at room temperature. The solvent is evaporated under reduced pressure and the residue is chromatographed on silica gel to give 4-(2-acetoxypropyl)-2-azetidinone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04348320 |
| Source dataset | uspto-grants-1982_09 |
| ORD ID | ord-58df5a2467e1470cb439226334001382 |
| Source note | uspto-grants-1982_09 |