Water → HCID 70522181, compound

Participants

Reaction Steps

Sodium borohydride (16 g) was added to a stirred solution of 3α-isobutyroxy-2β,16β-dipiperidino-5α-androstan-17-one (51.6 g) in methylene dichloride (150 ml) and methanol (150 ml) and the reaction mixture was stirred for a further hour. Water was added, the product extracted with ether, and the extract washed well with water and dried. Concentration of the ether solution yielded 2β,16β-dipiperidino-5α-androstan-3α,17β-diol 3-isobutyrate (21 g) which was recrystallised from ether.

Provenance & Evidence