Diazomethane → HCID 54063524, compound

HRID 1702611Notes

Reaction equation

HRID 1702611 reaction equation
[N+:1]([C:4]1[CH:12]=[CH:11][C:10]([CH3:13])=[CH:9][C:5]=1[C:6]([OH:8])=[S:7])([O-:3])=[O:2].[N+](=[CH2:16])=[N-]>CO>[N+:1]([C:4]1[CH:12]=[CH:11][C:10]([CH3:13])=[CH:9][C:5]=1[C:6]([O:8][CH3:16])=[S:7])([O-:3])=[O:2]

Participants

4

Reactant 2

HCID 9550DiazomethaneHCID 178426720HCID 178426720, compound

Product 1

HCID 54063524HCID 54063524, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To an ice cold solution of 52.1 g. of 2-nitro-5-methylthiobenzoic acid in 250 ml. of methanol was added an ethereal solution of diazomethane until thin layer chromatography indicated the reaction was complete. The resulting solution was evaporated to dryness and used as such. In one case the crude product was crystallized from methanol to give yellow needles of methyl 2-nitro-5-methylthiobenzoate, mp 53°-54°.

Workup

  1. customThe resulting solution was evaporated to dryness
  2. customIn one case the crude product was crystallized from methanol

Sources & evidence

ORD record
ord-35b36658163442008ad15e951906f8a8
Source dataset
uspto-grants-1982_09
Patent number
US04348396

Reaction notes

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