Azobisisobutyronitrile → HCID 20526235, compound

Participants

Reaction Conditions

Reaction Steps

37.5 parts of methyl 2-(2',4'-dichlorophenoxy)-propionate and 26.7 parts of N-bromosuccinimide in 300 parts of carbon tetrachloride are boiled under reflux, 0.1 part of azo-bis-isobutyronitrile being added every 45 minutes. The mixture is refluxed until the succinimide formed floats on the solvent. A total reaction time of 10 hours is required. The mixture is then cooled to 0° C. and filtered, and the filtrate is concentrated under reduced pressure. 36.9 parts (82% of theory) of methyl 2-bromo-2-(2',4'-dichlorophenoxy)-propionate, of nD22 =1.5395, are obtained.

Provenance & Evidence