Hydrochloric Acid → HCID 20525737, compound

Participants

Reaction Steps

A mixture of 10.0 g. of ethyl 4-(hexadecylamino)hydrocinnamate, 50 ml. of pyridine and 25 ml. of acetic anhydride is heated on a steam bath for 15 hours. The solution is poured onto ice and adjusted to pH 6 with concentrated hydrochloric acid. The mixture is filtered and the crystals washed with water. The solid is recrystallized from ethanol, yielding ethyl 4-(N-hexadecylacetamido)hydrocinnamate.

Provenance & Evidence