HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4-Dichlorobenzotrifluoride → 3-(2'-Chloro-4-trifluoromethylphenoxy)-6-chlorothioanisole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4-Dichlorobenzotrifluoride | HCID 9481 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 4-Chloro-3-(methylthio)phenol | HCID 21877186 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | 3-(2'-Chloro-4-trifluoromethylphenoxy)-6-chlorothioanisole | HCID 20524737 | 80.1% |
Reaction Steps
50 g of 4-chloro-3-methylmercaptophenol, 62 g of 3,4-dichlorobenzotrifluoride and 12 g of sodium hydroxide are stirred in 150 ml of dimethyl sulphoxide for 6 hours at 142° C. The reaction mixture is then poured onto ice and extracted with toluene. Distillation of the organic phase yields 81 g of 3-(2'-chloro-4-trifluoromethylphenoxy)-6-chlorothioanisole with a boiling point of 158° C./0.4 mbar.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04349377 |
| Source dataset | uspto-grants-1982_09 |
| ORD ID | ord-b17eee9299504d18a4c2c398e032ba2d |
| Source note | uspto-grants-1982_09 |