Methyl Isocyanate → HCID 20525165, compound

Participants

Reaction Steps

5.7 g (0.1 mol) of methyl isocyanate and a few drops of dibutyl-tin dilaurate were added, while stirring, to 25.8 g (0.1 mol) of 1-(2,4-dichlorophenyl)-1-hydroxy-2-(1,2,4-triazol-1-yl)-ethane in 250 ml of ethyl acetate. The mixture was stirred overnight at 60°-65° C. It was then allowed to cool and the crystalline precipitate was filtered off and washed with ether. 30.4 g (97% of theory) of 1-(2,4-dichlorophenyl)-1-methylcarbamoyloxy-2-(1,2,4-triazol-1-yl)-ethane of melting point 204° C. were obtained.

Provenance & Evidence