Thionyl Chloride → HCID 20525194, compound

HRID 1702768Notes

Reaction equation

HRID 1702768 reaction equation
O[C:2]1([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=2[CH3:20])[C:13]2[CH:12]=[CH:11][S:10][C:9]=2[C:8]2[C:3]1=[CH:4][CH:5]=[CH:6][CH:7]=2.S(Cl)([Cl:23])=O>C1C=CC=CC=1>[Cl:23][C:2]1([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=2[CH3:20])[C:13]2[CH:12]=[CH:11][S:10][C:9]=2[C:8]2[C:3]1=[CH:4][CH:5]=[CH:6][CH:7]=2

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 12773634HCID 12773634, compound

Product 1

HCID 20525194HCID 20525194, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

5.6 g (20 mmoles) of 4-hydroxy-4-(2-methyl-phenyl)-4H-indeno[1,2-b]thiophene were dissolved in 40 ml of absolute benzene, and 34 ml of thionyl chloride were added. The mixture was heated under reflux for 5 hours. The reaction solution was then evaporated in vacuo, the oily residue was taken up in cyclohexane, the insoluble material was filtered off and the clear filtrate was evaporated again in vacuo. 6.1 g of crude 4-chloro-4-(2-methyl-phenyl)-4H-indeno[1,2-b]thiophene were obtained as a viscous oil, which was further reacted directly. ##STR11##

Workup

  1. temperatureThe mixture was heated
  2. temperatureunder reflux for 5 hours
  3. customThe reaction solution was then evaporated in vacuo
  4. filtrationthe insoluble material was filtered off
  5. customthe clear filtrate was evaporated again in vacuo

Sources & evidence

ORD record
ord-a70147e007844951b5f2760008362695
Source dataset
uspto-grants-1982_09
Patent number
US04349560

Reaction notes

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