HuagongsheHuagongshe Chemistry Print Report · For research reference only
alpha Lipoic acid → HCID 20525121, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | alpha Lipoic acid | HCID 864 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | P,P-Diphenylphosphinic azide | HCID 199401 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | HCID 20525121 | HCID 20525121 | — |
Reaction Steps
The reaction of 5-(1,2-dithiolan-3-yl)pentanoic acid and diphenylphosphoryl azide in a solution of triethyl amine and benzene provided a solution comprising 4-(1,2-dithiolan-3-yl)butyl isocyanate (I.R.: 2270 cm-1), which was reacted with 5-fluorouracil to provide 1-[N-[4-(1,2-dithiolan-3-yl)butyl]carbamoyl]-5-fluorouracil substantially in the similar method to that of Example 13.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04349552 |
| Source dataset | uspto-grants-1982_09 |
| ORD ID | ord-c3ae2a0e956d40dca2a9a988caed5f81 |
| Source note | uspto-grants-1982_09 |