Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 3,4-Dichlorophenol | HCID 7258 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Benzene, 1,2-dichloro-4-(methylsulfonyl)- | HCID 161963 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 13078530 | HCID 13078530 | 82.4% |
Reaction Steps
To a solution of 9.09 g (0.0558 mole) of 3,4-dichlorophenol dissolved in 150 ml of DMSO was added 2.23 g (0.0558 mole) of NaOH. The mixture was heated to 60° C. and 11.3 g (0.0502 mole) of 3,4-dichlorophenyl methyl sulfone was added and the mixture heated at 150° C. for 3.75 hrs. The mixture was cooled and poured into water. The crystalline product was collected by filtration, washed with water and dried, which gave 14.5 g (82.4% yield) of product. Recrystallization from ethanol afforded purified 4-(2-chloro-4-(methylsulfonyl)phenoxy)-1,2-dichlorobenzene, mp 102°-104° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04349568 |
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| Source dataset | uspto-grants-1982_09 |
|---|
| ORD ID | ord-75cb133bbd79402a90f66cb778981c33 |
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| Source note | uspto-grants-1982_09 |
|---|
