HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → 8-[3-(4-Fluorophenyl)-2-oxo-4-phenyl-4-imidazolin-1-yl] caprylic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | Methyl 8-bromooctanoate | HCID 11107373 | — |
| Reactant | 1-(4-Fluorophenyl)-5-phenyl-4-imidazolin-2-one | HCID 20525406 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 8-[3-(4-Fluorophenyl)-2-oxo-4-phenyl-4-imidazolin-1-yl] caprylic acid methyl ester | HCID 54265547 | — |
Reaction Steps
The product is product as described in example 1 from 2.16 g of NaH (80% suspension in mineral oil), 18.3 g of 1-(4-Fluorophenyl)-5-phenyl-4-imidazolin-2-one, 150 cc. of DMF, 17.1 g of 8-bromocaprylic acid methyl ester and 2.16 g of NaJ.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04349684 |
| Source dataset | uspto-grants-1982_09 |
| ORD ID | ord-592b58caba3e46de9b7c42c880e694b2 |
| Source note | uspto-grants-1982_09 |