Sodium Hydroxide → 7-(3-Ethyl-4.5-diphenyl-2-oxo-4-imidazolin-1-yl) enanthic acid

HRID 1702899Notes

Reaction equation

HRID 1702899 reaction equation
C([O:3][C:4](=[O:31])[CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][N:11]1[C:15]([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)=[C:14]([C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[N:13]([CH2:28][CH3:29])[C:12]1=[O:30])C.[OH-].[Na+]>C(O)C>[CH2:28]([N:13]1[C:14]([C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)=[C:15]([C:16]2[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=2)[N:11]([CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][C:4]([OH:31])=[O:3])[C:12]1=[O:30])[CH3:29]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 537087157-(3-Ethyl-4.5-diphenyl-2-oxo-4-imidazolin-1-yl) enanthic acid ethyl ester

Product 1

HCID 129617147-(3-Ethyl-4.5-diphenyl-2-oxo-4-imidazolin-1-yl) enanthic acid

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The product is produced as described in example 18 from 12.3 g of 7-(3-ethyl-4.5-diphenyl-2-oxo-4-imidazolin-1-yl) enanthic acid ethyl ester and 1.16 g of NaOH in 60 cc. of ethanol. Further purification by chromatography on silicic acid gel using chloroform as eluant.

Workup

  1. customThe product is produced
  2. customFurther purification by chromatography on silicic acid gel

Sources & evidence

ORD record
ord-a51f3f72ca1a488c9fcb9a06e75d56f7
Source dataset
uspto-grants-1982_09
Patent number
US04349684

Reaction notes

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