Sodium Hydroxide → HCID 12961717, compound

HRID 1702902Notes

Reaction equation

HRID 1702902 reaction equation
C[O:2][C:3](=[O:33])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][N:11]1[CH:15]=[C:14]([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[N:13]([C:22]2[CH:27]=[CH:26][CH:25]=[C:24]([C:28]([F:31])([F:30])[F:29])[CH:23]=2)[C:12]1=[O:32].[OH-].[Na+]>CO>[O:32]=[C:12]1[N:13]([C:22]2[CH:27]=[CH:26][CH:25]=[C:24]([C:28]([F:31])([F:29])[F:30])[CH:23]=2)[C:14]([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)=[CH:15][N:11]1[CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][C:3]([OH:33])=[O:2]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 53874415HCID 53874415, compound

Product 1

HCID 12961717HCID 12961717, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The product is produced as described in example 18 from 6.9 g of 8-[2-oxo-4-phenyl-3-(3-trifluoromethyl-phenyl)-4-imidazolin-1-yl] caprylic acid methyl ester and 0.66 g of NaOH in 30 cc. of methanol. Further purification by chromatography on silicic acid gel using chloroform as eluant.

Workup

  1. customThe product is produced
  2. customFurther purification by chromatography on silicic acid gel

Sources & evidence

ORD record
ord-beb655bac50243d1ba913ca925ddfc60
Source dataset
uspto-grants-1982_09
Patent number
US04349684

Reaction notes

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