Sodium Hydroxide → HCID 12961724, compound

HRID 1702907Notes

Reaction equation

HRID 1702907 reaction equation
C[O:2][C:3](=[O:32])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][N:11]1[C:15]([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=2[F:22])=[C:14]([C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][C:24]=2[F:29])[N:13]([CH3:30])[C:12]1=[O:31].[OH-].[Na+]>CO>[F:29][C:24]1[CH:25]=[CH:26][CH:27]=[CH:28][C:23]=1[C:14]1[N:13]([CH3:30])[C:12](=[O:31])[N:11]([CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][C:3]([OH:32])=[O:2])[C:15]=1[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=1[F:22]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 53902604HCID 53902604, compound

Product 1

HCID 12961724HCID 12961724, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The product is produced as described in example 18 from 5.2 g of 8-[4.5-bis-(2-fluorophenyl)-3-methyl-2-oxo-4-imidazolin-1-yl] caprylic acid methyl ester and 0.53 g of NaOH in 25 cc. of methanol. Recrystallization from ether/hexane.

Workup

  1. customThe product is produced
  2. customRecrystallization from ether/hexane

Sources & evidence

ORD record
ord-fdd4ab4bfa694b6aab0a216c15517cc3
Source dataset
uspto-grants-1982_09
Patent number
US04349684

Reaction notes

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