Sodium Hydroxide → 9-[3-(4-Chlorophenyl)-2-oxo-4-phenyl-4-imidazolin-1-yl] pelargonic acid

HRID 1702909Notes

Reaction equation

HRID 1702909 reaction equation
C[O:2][C:3](=[O:31])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][N:12]1[CH:16]=[C:15]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[N:14]([C:23]2[CH:28]=[CH:27][C:26]([Cl:29])=[CH:25][CH:24]=2)[C:13]1=[O:30].[OH-].[Na+]>CO>[Cl:29][C:26]1[CH:27]=[CH:28][C:23]([N:14]2[C:15]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)=[CH:16][N:12]([CH2:11][CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][C:3]([OH:31])=[O:2])[C:13]2=[O:30])=[CH:24][CH:25]=1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 129617119-[3-(4-Chlorophenyl)-2-oxo-4-phenyl-4-imidazolin-1-yl] pelargonic acid methyl ester

Product 1

HCID 129617269-[3-(4-Chlorophenyl)-2-oxo-4-phenyl-4-imidazolin-1-yl] pelargonic acid

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The product is produced as described in example 18 from 4.4 g of 9-[3-(4-chlorophenyl)-2-oxo-4-phenyl-4-imidazolin-1-yl] pelargonic acid methyl ester and 0.4 g of NaOH in 20 cc. of methanol. Further purification by chromatography on silicic acid gel using chloroform as eluant.

Workup

  1. customThe product is produced
  2. customFurther purification by chromatography on silicic acid gel

Sources & evidence

ORD record
ord-b34f8abfafb845369a006d1eefc8445b
Source dataset
uspto-grants-1982_09
Patent number
US04349684

Reaction notes

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