Carbon Disulfide → HCID 13050833, compound

HRID 1702913Notes

Reaction equation

HRID 1702913 reaction equation
[C:1]1([CH2:6][NH2:7])([CH2:4][NH2:5])[CH2:3][CH2:2]1.[C:8](=S)=[S:9]>>[CH2:3]1[C:1]2([CH2:6][NH:7][C:8](=[S:9])[NH:5][CH2:4]2)[CH2:2]1

Participants

3

Reactant 2

HCID 6348Carbon DisulfideHCID 13050832HCID 13050832, compound

Product 1

HCID 13050833HCID 13050833, compound

Procedure

By the above reaction scheme, 1,1-cyclopropanedimethanamine is reacted with carbon disulfide to yield 5,7-diazaspiro[2.5]octane-6-thione. Alkylation of this thione with methyl iodide affords 6-(methylthio)-5,7-diazaspiro[2.5]-oct-5-ene, hydriodide. Reaction of this compound with hydrazine hydrate yields 6-hydrazino-5,7-diazaspiro[2.5]oct-5-ene hydriodide. Finally, condensation of this hydrazine with 1,5-bis(α,α,α-trifluoro-p-tolyl)-1,4-pentadien-3-one yields the desired formula (1) compound: 1,5-bis(α,α,α-trifluoro-p-tolyl)-1,4-pentadien-3-one 5,7-diazaspiro[2.5]-oct-5-en-6-ylhydrazone.

Sources & evidence

ORD record
ord-532f87b83947421193e2059bc90491a9
Source dataset
uspto-grants-1982_09
Patent number
US04349553

Reaction notes

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