HuagongsheHuagongshe Chemistry Print Report · For research reference only
1H-Indole-3-propanamide, N-methyl- → HCID 21472501, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1H-Indole-3-propanamide, N-methyl- | HCID 7661699 | — |
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 21472501 | HCID 21472501 | — |
Reaction Steps
A solution of 60.6 g 3-(3-indolyl)-N-methyl-propionamide in 500 ml anhydrous tetrahydrofuran are added dropwise at 25° for 15 minutes under nitrogen atmosphere to a suspension of 34.2 g lithium aluminium hydride in 800 ml anhydrous tetrahydrofuran and maintained at 66° for 3 hours. N-methyl-3-(3-indolyl)-propylamine (M.pt 81°-82° after crystallization from methylene chloride/ethyl acetate) is obtained after working up.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04350634 |
| Source dataset | uspto-grants-1982_09 |
| ORD ID | ord-32347f998b68432dbcbb537f83dfde11 |
| Source note | uspto-grants-1982_09 |