Acrylonitrile → HCID 70545066, compound

HRID 1702924Notes

Reaction equation

HRID 1702924 reaction equation
[CH3:1][NH:2][CH2:3][CH2:4][CH2:5][C:6]1[C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[NH:8][CH:7]=1.[C:15](#[N:18])[CH:16]=[CH2:17]>COCCOC>[C:15]([CH2:16][CH2:17][N:2]([CH2:3][CH2:4][CH2:5][C:6]1[C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[NH:8][CH:7]=1)[CH3:1])#[N:18]

Participants

4

Reactant 2

HCID 7855AcrylonitrileHCID 21472501HCID 21472501, compound

Product 1

HCID 70545066HCID 70545066, compound

Reagents, catalysts & solvents 1

HCID 80711,2-DimethoxyethaneSolvent

Procedure

A mixture of 37.6 g N-methyl-3-(3-indolyl)-propylamine and 21, 2 g acrylonitrile in 65 ml anhydrous 1,2-dimethoxyethane are warmed with stirring at 60°0 for 21/2 hours. N-(2-cyanoethyl-N-methyl-3-(3-indolyl)propylamine (M.pt 48°-49° after crystallization from isopropyl ether) is obtained after working up.

Workup

  1. temperatureare warmed

Sources & evidence

ORD record
ord-cede7e5845454aeab9c7bae4af34152d
Source dataset
uspto-grants-1982_09
Patent number
US04350634

Reaction notes

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