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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1702966Generated: October 25, 2026

2-Phenylcyclopentanone → Cypenamine

https://huagongshe.com/reaction/1702966

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-PhenylcyclopentanoneHCID 290154—
ReactantAmmonium formateHCID 2723923—
ProductCypenamineHCID 21786—

Reaction Steps

2-Phenylcyclopentanone is reacted with ammonium formate at 170° C. via the Leuckart method to afford predominantly the cis isomer of 2-phenylcyclopentylamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04350685
Source datasetuspto-grants-1982_09
ORD IDord-75da60f633e84fc982f54c164e0a00b9
Source noteuspto-grants-1982_09