N,N'-Dimethylurea → HCID 12876411, compound

HRID 1702990Notes

Reaction equation

HRID 1702990 reaction equation
[CH3:1][NH:2][C:3]([NH:5][CH3:6])=[O:4].[C:7]1([N:13]=[C:14]=[O:15])[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1>O1CCOCC1>[CH3:1][NH:2][C:3]([N:5]([CH3:6])[C:14]([NH:13][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)=[O:15])=[O:4]

Participants

4

Reactant 2

HCID 7293N,N'-DimethylureaHCID 7672Phenyl isocyanate

Product 1

HCID 12876411HCID 12876411, compoundYield 60.3%

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

In 50 ml of anhydrous dioxane, 3.5 g (0.04 mol) of 1,3-dimethyl urea was dissolved, and under stirring 4.8 g (0.04 mol) of phenylisocyanate was added thereinto. The reaction was carried out at a room temperature for 15 hours, then the reaction mixture was treated a procedure same as in Example 1. The residue thus obtained was recrystallized from ethanol-petroleum ether to obtain 5.0 g (yield 60%) of 1,3-dimethyl-5-phenylbiuret having a melting point of 93°-95° C.

Workup

  1. additionwas added
  2. additionthe reaction mixture was treated a procedure same as in Example 1
  3. customThe residue thus obtained
  4. customwas recrystallized from ethanol-petroleum ether

Sources & evidence

ORD record
ord-32489b77657d4a1e86b379f54598bcc2
Source dataset
uspto-grants-1982_09
Patent number
US04350700

Reaction notes

Loading…