Sodium Hydroxide → HCID 53637955, compound

HRID 1703010Notes

Reaction equation

[CH3:1][O:2][N:3]=[C:4]([C:10]1[S:11][C:12]([CH3:15])=[N:13][N:14]=1)[C:5]([O:7]CC)=[O:6].[OH-].[Na+]>>[CH3:1][O:2][N:3]=[C:4]([C:10]1[S:11][C:12]([CH3:15])=[N:13][N:14]=1)[C:5]([OH:7])=[O:6]

Participants

Reactant 2

HCID 14798Sodium Hydroxide

HCID 54048893HCID 54048893, compound

Product 1

HCID 53637955HCID 53637955, compoundYield 71.2%

Procedure

Ethyl 2-methoxyimino-2-(5-methyl-1,3,4-thiadiazol-2-yl)acetate (syn isomer) (0.4 g.) and 1 N aqueous solution of sodium hydroxide (2.1 ml.) were treated according to a similar manner to that of Example 1(a) (5) to give 2-methoxyimino-2-(5-methyl-1,3,4-thiadiazol-2-yl)acetic acid (syn isomer) (0.25 g.), mp 168° to 171° C. (dec.).

Sources & evidence

ORD record: ord-8182e18033d14021a6e6f63d6a5744ca
Source dataset: uspto-grants-1982_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04350693

Reaction notes

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