Hydrochloric Acid → HCID 131712847, compound

Participants

Reaction Steps

Alternatively, 0.10 g peptide ester (16) are suspended in 5 ml H2O and 3 ml methyl alcohol and saponified with 0.32 ml 1 N NaOH for 90 min. at room temperature. 0.32 ml 1 N HCl are added, and the solution concentrated in vacuo. By dilution with 95% ethanol 0.08 g of the title compound (17) is obtained, m.p. 250°-252° C. (dec.); [α]D28 -2.8° (C=1, DMF), RfC =0.56. Amino acid ratios: Gly 1.04; ala 0.94; Tyr 1.00; Phe 1.05.

Provenance & Evidence