HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formaldehyde → 1H-Benzotriazole-1-methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formaldehyde | HCID 712 | — |
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 178418385 | HCID 178418385 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 1H-Benzotriazole-1-methanol | HCID 224169 | — |
Reaction Steps
A slurry of benzotriazole (11.9 g) and 30% formalin (8.3 ml) was heated to reflux in 100 ml of 25% aqueous dimethylformamide. A trace of starting material remained. The solution was treated with 1.0 ml of 10% aqueous sodium hydroxide and heated to reflux again. An aqueous ethyl acetate extractive work up afforded 1-(hydroxymethyl)benzotriazole (8.65 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04350752 |
| Source dataset | uspto-grants-1982_09 |
| ORD ID | ord-d3c2af53391b491794bf18de849f3f96 |
| Source note | uspto-grants-1982_09 |