HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 5-(Chloromethyl)uracil
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 5-(Hydroxymethyl)uracil | HCID 78168 | — |
| Product | 5-(Chloromethyl)uracil | HCID 236125 | — |
Reaction Steps
A solution of 1.4 g. (0.010 mole) of 5-hydroxymethyl uracil in 12.5 ml. of concentrated hydrochloric acid was prepared. A colorless precipitate (5-chloromethyl uracil) formed within two minutes and after about ten minutes the precipitate was collected by filtration, washed rapidly with ice cold water, dried and then suspended in 10 ml. of dimethylformamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04350754 |
| Source dataset | uspto-grants-1982_09 |
| ORD ID | ord-4dcebf16c68b4e21871e38c7da8478f6 |
| Source note | uspto-grants-1982_09 |