Pyridine → HCID 23460501, compound

HRID 1703056Notes

Reaction equation

HRID 1703056 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]=[C:7]([CH3:12])[C:6]1[C:13](O[C:16](=[O:17])[C:5]2=1)=[O:14].[N:18]1C=CC=C[CH:19]=1>>[O:17]=[C:16]1[C:5]2[C:4]3[CH:3]=[C:2]([Br:1])[CH:11]=[CH:10][C:9]=3[N:8]=[C:7]([CH3:12])[C:6]=2[C:13](=[O:14])[N:18]1[CH3:19]

Participants

3

Reactant 2

HCID 1049PyridineHCID 15154343HCID 15154343, compound

Product 1

HCID 23460501HCID 23460501, compound

Procedure

To 350 ml of dry pyridine was added 14.7 g of the anhydride (ix) in a 3-neck flask with reflux condenser, drying tube, magnetic stirrer and a thermometer. The flask was cooled with an ice/H2O bath and dry reagent grade CH3NH2 was passed into the mixture. The flask was then allowed to warm up to room temperature and refluxed for 20 hours.

Workup

  1. temperaturewith reflux condenser
  2. customdrying tube, magnetic stirrer
  3. temperatureThe flask was cooled with an ice/H2O bath
  4. temperaturerefluxed for 20 hours

Sources & evidence

ORD record
ord-464737e1fdd84a718bceef91d1a83022
Source dataset
uspto-grants-1982_09
Patent number
US04350814

Reaction notes

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