HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 4-[(3-Phenylprop-2-en-1-yl)amino]benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | Water ethanol | HCID 19096565 | — |
| Reactant | Ethyl 4-[(3-phenylprop-2-en-1-yl)amino]benzoate | HCID 53948325 | — |
| Solvent | Water | HCID 962 | — |
| Product | 4-[(3-Phenylprop-2-en-1-yl)amino]benzoic acid | HCID 54537106 | — |
Reaction Steps
A mixture of 10 g. of ethyl p-(cinnamylamino)benzoate (prepared as described in Example 24), 10 g. of potassium hydroxide and 200 ml. of ethanol-water (9:1) is refluxed for 3 hours. The solution is acidified while hot with concentrated hydrochloric acid, diluted with water, cooled and filtered to give off-white crystals. Recrystallization from ethanol gives pale yellow crystals, m.p. 200°-202° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04350822 |
| Source dataset | uspto-grants-1982_09 |
| ORD ID | ord-d6dda8e022394d429dfc6664585108b7 |
| Source note | uspto-grants-1982_09 |