HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 4-({[4-(Heptyloxy)phenyl]methyl}amino)benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | Ethyl 4-({[4-(heptyloxy)phenyl]methyl}amino)benzoate | HCID 13079688 | — |
| Solvent | Water | HCID 962 | — |
| Product | 4-({[4-(Heptyloxy)phenyl]methyl}amino)benzoic acid | HCID 13079687 | — |
Reaction Steps
A mixture of 5 g. of ethyl p-[p-(heptyloxy)benzyl]amino benzoate (prepared as described in Example 54), 1.51 g. of potassium hydroxide and 50 ml. of 95% ethanol is refluxed for 5 hours. Concentrated hydrochloric acid is added and the mixture diluted with 150 ml. of water. Chilling and filtering gives crystals which are recrystallized from ethanol to give white crystals, m.p. 148°-152.5° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04350822 |
| Source dataset | uspto-grants-1982_09 |
| ORD ID | ord-8281fe83063f4141b6905f25d32b3da9 |
| Source note | uspto-grants-1982_09 |