HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoic acid, 3,4,5-trimethoxy-2-nitro-, methyl ester → Methyl 3,4,5-trimethoxyanthranilate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoic acid, 3,4,5-trimethoxy-2-nitro-, methyl ester | HCID 78765 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Catalyst | HCID 178418361 | HCID 178418361 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Methyl 3,4,5-trimethoxyanthranilate | HCID 78735 | 92.6% |
Reaction Steps
The latter nitro derivative (17.0 g) in 500 ml of methanol was reduced at room temperature and pressure with hydrogen using 4 g of 10% palladium on carbon as catalyst for 6 hr and filtered. The solvent was removed to give 14 g of 2-amino-3,4,5-trimethoxybenzoic acid methyl ester as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04351832 |
| Source dataset | uspto-grants-1982_09 |
| ORD ID | ord-08dd9168198d407b9624796252fff69c |
| Source note | uspto-grants-1982_09 |